Comparative study of platelet aggregation by turbidimetric and impedance methods in patients under acetylsalicylic acid antiplatelet therapy
نویسندگان
چکیده
Introduction: Hyperaggregation of platelets can cause the formation of thrombi and subsequent occlusion of blood vessels leading to ischemia. This phenomenon can be responsible for ischemic cardiovascular diseases such as angina pectoris, atherosclerosis, stroke and other forms of ischemia. To decrease platelet function and reduce the formation of thrombi, acetylsalicylic acid has been used for antithrombotic treatment, with several studies showing its effectiveness. Therefore it is necessary to use a laboratory tool to monitor the effectiveness of treatment, which is achieved through laboratory testing of platelet aggregation. Method: Two different examinations (impedance and turbidimetry) were compared in 30 adult patients of both genders taking acetylsalicylic acid. Conclusion: The results show that there is a good correlation between these two methods and so both these techniques can be used in the clinical routine.
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